2iln

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==Crystal structure of the Bowman-Birk inhibitor from snail medic seeds in complex with bovine trypsin==
==Crystal structure of the Bowman-Birk inhibitor from snail medic seeds in complex with bovine trypsin==
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<StructureSection load='2iln' size='340' side='right' caption='[[2iln]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2iln' size='340' side='right'caption='[[2iln]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iln]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin] and [http://en.wikipedia.org/wiki/Medsc Medsc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ILN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ILN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iln]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Medicago_scutellata Medicago scutellata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ILN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ILN FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mvz|1mvz]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iln OCA], [https://pdbe.org/2iln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iln RCSB], [https://www.ebi.ac.uk/pdbsum/2iln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iln ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iln OCA], [http://pdbe.org/2iln PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iln RCSB], [http://www.ebi.ac.uk/pdbsum/2iln PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iln ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IBB_MEDSC IBB_MEDSC]] Inhibits trypsin but not chymotrypsin. Inhibits the trypsin-like proteinase activity present in larvae of the crop pests Adoxophyes orana, Hyphantria cunea, Lobesia botrana and Ostrinia nubilalis.<ref>PMID:9014368</ref>
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/il/2iln_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/il/2iln_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
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[[Category: Medsc]]
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[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Capaldi, S]]
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[[Category: Carrizo, M E]]
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[[Category: Faggion, B]]
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[[Category: Monaco, H L]]
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[[Category: Perduca, M]]
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[[Category: Ragona, L]]
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[[Category: Tava, A]]
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[[Category: Bowman-birk inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Medicago scutellata]]
[[Category: Medicago scutellata]]
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[[Category: Protease inhibitor]]
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[[Category: Capaldi S]]
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[[Category: Carrizo ME]]
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[[Category: Faggion B]]
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[[Category: Monaco HL]]
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[[Category: Perduca M]]
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[[Category: Ragona L]]
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[[Category: Tava A]]

Current revision

Crystal structure of the Bowman-Birk inhibitor from snail medic seeds in complex with bovine trypsin

PDB ID 2iln

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