1yz4

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[[Image:1yz4.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of DUSP15==
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|PDB= 1yz4 |SIZE=350|CAPTION= <scene name='initialview01'>1yz4</scene>, resolution 2.4&Aring;
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<StructureSection load='1yz4' size='340' side='right'caption='[[1yz4]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1yz4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YZ4 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz4 OCA], [https://pdbe.org/1yz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yz4 RCSB], [https://www.ebi.ac.uk/pdbsum/1yz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yz4 ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz4 OCA], [http://www.ebi.ac.uk/pdbsum/1yz4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yz4 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/DUS15_HUMAN DUS15_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/1yz4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yz4 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of DUSP15'''
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==See Also==
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*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]]
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*[[MAP kinase phosphatase|MAP kinase phosphatase]]
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==About this Structure==
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__TOC__
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1YZ4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ4 OCA].
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</StructureSection>
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==Reference==
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Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase., Yoon TS, Jeong DG, Kim JH, Cho YH, Son JH, Lee JW, Ryu SE, Kim SJ, Proteins. 2005 Nov 15;61(3):694-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16170801 16170801]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Cho YH]]
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[[Category: Cho, Y H.]]
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[[Category: Jeong DG]]
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[[Category: Jeong, D G.]]
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[[Category: Jeong SK]]
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[[Category: Jeong, S K.]]
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[[Category: Kim JH]]
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[[Category: Kim, J H.]]
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[[Category: Kim SJ]]
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[[Category: Kim, S J.]]
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[[Category: Lee JW]]
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[[Category: Lee, J W.]]
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[[Category: Ryu SE]]
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[[Category: Ryu, S E.]]
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[[Category: Son JH]]
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[[Category: Son, J H.]]
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[[Category: Yoon TS]]
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[[Category: Yoon, T S.]]
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[[Category: hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:26:41 2008''
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Current revision

Crystal structure of DUSP15

PDB ID 1yz4

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