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1l1q

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==Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine==
==Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine==
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<StructureSection load='1l1q' size='340' side='right' caption='[[1l1q]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='1l1q' size='340' side='right'caption='[[1l1q]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1l1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Giain Giain]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L1Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1l1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L1Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9DA:9-DEAZAADENINE'>9DA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l1r|1l1r]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9DA:9-DEAZAADENINE'>9DA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenine_phosphoribosyltransferase Adenine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.7 2.4.2.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l1q OCA], [https://pdbe.org/1l1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l1q RCSB], [https://www.ebi.ac.uk/pdbsum/1l1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l1q ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l1q OCA], [http://pdbe.org/1l1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l1q RCSB], [http://www.ebi.ac.uk/pdbsum/1l1q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l1q ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q967M2_GIAIN Q967M2_GIAIN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/1l1q_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/1l1q_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1l1q" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1l1q" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenine phosphoribosyltransferase]]
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[[Category: Giardia intestinalis]]
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[[Category: Giain]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Sarver, A E]]
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[[Category: Sarver AE]]
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[[Category: Schramm, V L]]
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[[Category: Schramm VL]]
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[[Category: Shi, W]]
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[[Category: Shi W]]
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[[Category: Tanaka, K S]]
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[[Category: Tanaka KS]]
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[[Category: Wang, C C]]
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[[Category: Wang CC]]
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[[Category: Adenine]]
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[[Category: Aprtase]]
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[[Category: Catalytic loop]]
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[[Category: Giardia lamblia]]
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[[Category: Purine metabolism]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine

PDB ID 1l1q

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