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1m7b

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==Crystal structure of Rnd3/RhoE: functional implications==
==Crystal structure of Rnd3/RhoE: functional implications==
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<StructureSection load='1m7b' size='340' side='right' caption='[[1m7b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1m7b' size='340' side='right'caption='[[1m7b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1m7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M7B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1m7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rnd3 (amino acids 19-200) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7b OCA], [http://pdbe.org/1m7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m7b RCSB], [http://www.ebi.ac.uk/pdbsum/1m7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7b OCA], [https://pdbe.org/1m7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7b RCSB], [https://www.ebi.ac.uk/pdbsum/1m7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RND3_HUMAN RND3_HUMAN]] Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
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[https://www.uniprot.org/uniprot/RND3_HUMAN RND3_HUMAN] Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7b_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7b_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Rho GTPase|Rho GTPase]]
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ahmadian, M R]]
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[[Category: Large Structures]]
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[[Category: Blumenstein, L]]
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[[Category: Ahmadian MR]]
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[[Category: Fiegen, D]]
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[[Category: Blumenstein L]]
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[[Category: Stege, P]]
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[[Category: Fiegen D]]
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[[Category: Vetter, I R]]
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[[Category: Stege P]]
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[[Category: Signaling protein]]
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[[Category: Vetter IR]]
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[[Category: Small gtpase]]
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Current revision

Crystal structure of Rnd3/RhoE: functional implications

PDB ID 1m7b

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