5sw3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:33, 6 March 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal Structure of TGT in complex with 3-Pyridinecarboxylic acid, 6-(dimethylamino)==
==Crystal Structure of TGT in complex with 3-Pyridinecarboxylic acid, 6-(dimethylamino)==
-
<StructureSection load='5sw3' size='340' side='right' caption='[[5sw3]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
+
<StructureSection load='5sw3' size='340' side='right'caption='[[5sw3]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5sw3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SW3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5sw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_ZM4_=_ATCC_31821 Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SW3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=46L:6-(DIMETHYLAMINO)PYRIDINE-3-CARBOXYLIC+ACID'>46L</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA-guanine(34)_transglycosylase tRNA-guanine(34) transglycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=46L:6-(DIMETHYLAMINO)PYRIDINE-3-CARBOXYLIC+ACID'>46L</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5sw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sw3 OCA], [http://pdbe.org/5sw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5sw3 RCSB], [http://www.ebi.ac.uk/pdbsum/5sw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5sw3 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sw3 OCA], [https://pdbe.org/5sw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sw3 RCSB], [https://www.ebi.ac.uk/pdbsum/5sw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sw3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
+
[https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
 +
 
 +
==See Also==
 +
*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Hassaan, E]]
+
[[Category: Large Structures]]
-
[[Category: Heine, A]]
+
[[Category: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821]]
-
[[Category: Klebe, G]]
+
[[Category: Hassaan E]]
-
[[Category: Guanine exchange enzyme]]
+
[[Category: Heine A]]
-
[[Category: Protein interface]]
+
[[Category: Klebe G]]
-
[[Category: Tgt]]
+
-
[[Category: Transferase]]
+
-
[[Category: Trna]]
+

Current revision

Crystal Structure of TGT in complex with 3-Pyridinecarboxylic acid, 6-(dimethylamino)

PDB ID 5sw3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5sw3"
Personal tools