1z32

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:03, 23 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1z32.gif|left|200px]]
 
-
{{Structure
+
==Structure-function relationships in human salivary alpha-amylase: Role of aromatic residues==
-
|PDB= 1z32 |SIZE=350|CAPTION= <scene name='initialview01'>1z32</scene>, resolution 1.60&Aring;
+
<StructureSection load='1z32' size='340' side='right'caption='[[1z32]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=AGL:4,6-DIDEOXY-4-AMINO-ALPHA-D-GLUCOSE'>AGL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=HMC:5-HYDROXYMETHYL-CHONDURITOL'>HMC</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>
+
<table><tr><td colspan='2'>[[1z32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z32 FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
|GENE= AMY1A, AMY1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGL:4,6-DIDEOXY-4-AMINO-ALPHA-D-GLUCOSE'>AGL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=HMC:5-HYDROXYMETHYL-CHONDURITOL'>HMC</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z32 OCA], [https://pdbe.org/1z32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z32 RCSB], [https://www.ebi.ac.uk/pdbsum/1z32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z32 ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[1smd|1SMD]], [[1mfv|1MFV]], [[1mfu|1MFU]], [[1q4n|1Q4N]], [[1nm9|1NM9]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z32 OCA], [http://www.ebi.ac.uk/pdbsum/1z32 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1z32 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/AMY1A_HUMAN AMY1A_HUMAN] Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308). Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308).<ref>PMID:12527308</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/1z32_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z32 ConSurf].
 +
<div style="clear:both"></div>
-
'''Structure-function relationships in human salivary alpha-amylase: Role of aromatic residues'''
+
==See Also==
-
 
+
*[[Amylase 3D structures|Amylase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
1Z32 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z32 OCA].
+
__TOC__
-
[[Category: Alpha-amylase]]
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Gyemant, G.]]
+
[[Category: Gyemant G]]
-
[[Category: Kandra, L.]]
+
[[Category: Kandra L]]
-
[[Category: Mishra, P J.]]
+
[[Category: Mishra PJ]]
-
[[Category: Ragunath, C.]]
+
[[Category: Ragunath C]]
-
[[Category: Ramasubbu, N.]]
+
[[Category: Ramasubbu N]]
-
[[Category: Sundar, K.]]
+
[[Category: Sundar K]]
-
[[Category: tim barrel]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:28:20 2008''
+

Current revision

Structure-function relationships in human salivary alpha-amylase: Role of aromatic residues

PDB ID 1z32

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1z32"
Personal tools