Nitrate reductase
From Proteopedia
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- | <StructureSection load='' size=' | + | <StructureSection load='' size='350' side='right' caption='Bacterial periplasmic dissimilatory nitrate reductase containing Fe4S4 cluster with Mo, NO3- and molybdepterin guanine nucleotide (PDB entry [[2jiq]])' scene='49/490062/Cv/3'> |
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
- | <scene name='49/490062/Cv/ | + | <scene name='49/490062/Cv/7'>Bacterial periplasmic dissimilatory nitrate reductase containing Fe4S4 cluster with Mo, NO3 and 2 molybdepterin guanine nucleotides</scene>. NAP active site includes a <scene name='49/490062/Cv/8'>six-coordinated Mo atom which coordinates to 2 MGD molecules and Cys140</scene>. The <scene name='49/490062/Cv/9'>NO3 molecule is guided to the active site by a funnel leading to the Mo atom</scene><ref>PMID:18327621</ref>. |
</StructureSection> | </StructureSection> | ||
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**[[1ogy]] - NAP + heme + MGD + Mo– ''Rhodobacter sphaeroides''<br /> | **[[1ogy]] - NAP + heme + MGD + Mo– ''Rhodobacter sphaeroides''<br /> | ||
**[[2nya]] - EcNAP + MGD + Mo – ''Escherichia coli''<br /> | **[[2nya]] - EcNAP + MGD + Mo – ''Escherichia coli''<br /> | ||
- | **[[3ml1]], [[3o5a]] - NAP catalytic subunit + NAPB + heme + MGD + Mo – ''Ralstonia eutropha'' | + | **[[3ml1]], [[3o5a]] - NAP catalytic subunit + NAPB + heme + MGD + Mo – ''Ralstonia eutropha''<br /> |
+ | **[[5yly]] – NR cytochrome b5 reductase domain + FAD – ''Ulva prolifera''<br /> | ||
*Bacterial respiratory NR | *Bacterial respiratory NR |
Current revision
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3D structures of nitrate reductase
Updated on 23-July-2019
References
- ↑ NICHOLAS DJ, NASON A. Molybdenum and nitrate reductase. II. Molybdenum as a constituent of nitrate reductase. J Biol Chem. 1954 Mar;207(1):353-60. PMID:13152110
- ↑ Najmudin S, Gonzalez PJ, Trincao J, Coelho C, Mukhopadhyay A, Cerqueira NM, Romao CC, Moura I, Moura JJ, Brondino CD, Romao MJ. Periplasmic nitrate reductase revisited: a sulfur atom completes the sixth coordination of the catalytic molybdenum. J Biol Inorg Chem. 2008 Mar 8;. PMID:18327621 doi:10.1007/s00775-008-0359-6