5l12
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant== | |
| + | <StructureSection load='5l12' size='340' side='right'caption='[[5l12]], [[Resolution|resolution]] 1.72Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5l12]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1106a Burkholderia pseudomallei 1106a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L12 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.716Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l12 OCA], [https://pdbe.org/5l12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l12 RCSB], [https://www.ebi.ac.uk/pdbsum/5l12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l12 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ISPF_BURP0 ISPF_BURP0] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | ||
| - | + | ==See Also== | |
| - | + | *[[MECDP synthase 3D structures|MECDP synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Burkholderia pseudomallei 1106a]] |
| - | [[Category: Blain | + | [[Category: Large Structures]] |
| - | [[Category: Hagen | + | [[Category: Blain JM]] |
| - | [[Category: Raneiri | + | [[Category: Hagen TJ]] |
| - | [[Category: Walter | + | [[Category: Horn JR]] |
| + | [[Category: Raneiri G]] | ||
| + | [[Category: Walter RL]] | ||
Current revision
Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant
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