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1z72

From Proteopedia

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[[Image:1z72.gif|left|200px]]
 
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{{Structure
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==Structure of a putative transcriptional regulator from Streptococcus pneumoniae==
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|PDB= 1z72 |SIZE=350|CAPTION= <scene name='initialview01'>1z72</scene>, resolution 1.45&Aring;
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<StructureSection load='1z72' size='340' side='right'caption='[[1z72]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1z72]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z72 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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|GENE= SP0716 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 Streptococcus pneumoniae TIGR4])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03070 TENA_THI-4], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0819 TenA]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [https://pdbe.org/1z72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB], [https://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z72 ProSAT], [https://www.topsan.org/Proteins/MCSG/1z72 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z72 OCA], [http://www.ebi.ac.uk/pdbsum/1z72 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1z72 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/A0A0H2UP67_STRPN A0A0H2UP67_STRPN] Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).[PIRNR:PIRNR003170]
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== Evolutionary Conservation ==
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'''Structure of a putative transcriptional regulator from Streptococcus pneumoniae'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z72_consurf.spt"</scriptWhenChecked>
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1Z72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z72 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Streptococcus pneumoniae tigr4]]
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</jmolCheckbox>
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[[Category: Abdullah, J.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z72 ConSurf].
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[[Category: Cuff, M E.]]
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<div style="clear:both"></div>
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[[Category: Joachimiak, A.]]
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__TOC__
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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</StructureSection>
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[[Category: Zhou, M.]]
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[[Category: Large Structures]]
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[[Category: mcsg]]
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[[Category: Streptococcus pneumoniae TIGR4]]
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[[Category: midwest center for structural genomic]]
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[[Category: Abdullah J]]
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[[Category: protein structure initiative]]
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[[Category: Cuff ME]]
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[[Category: psi]]
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[[Category: Joachimiak A]]
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[[Category: streptococcus pneumoniae]]
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[[Category: Zhou M]]
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[[Category: structural genomic]]
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[[Category: transcription regulator]]
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[[Category: transcriptional regulator]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:30:24 2008''
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Current revision

Structure of a putative transcriptional regulator from Streptococcus pneumoniae

PDB ID 1z72

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