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5y1z

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==Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain==
==Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain==
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<StructureSection load='5y1z' size='340' side='right' caption='[[5y1z]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
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<StructureSection load='5y1z' size='340' side='right'caption='[[5y1z]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5y1z]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y1Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5y1z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y1Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.676&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1z OCA], [http://pdbe.org/5y1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y1z RCSB], [http://www.ebi.ac.uk/pdbsum/5y1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1z ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1z OCA], [https://pdbe.org/5y1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y1z RCSB], [https://www.ebi.ac.uk/pdbsum/5y1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DREB_HUMAN DREB_HUMAN]] Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS.<ref>PMID:20215400</ref>
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[https://www.uniprot.org/uniprot/DREB_HUMAN DREB_HUMAN] Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS.<ref>PMID:20215400</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, J]]
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[[Category: Homo sapiens]]
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[[Category: Liu, H]]
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[[Category: Large Structures]]
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[[Category: Liu, W]]
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[[Category: Li J]]
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[[Category: Wan, J]]
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[[Category: Liu H]]
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[[Category: Yao, N]]
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[[Category: Liu W]]
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[[Category: Zhang, M]]
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[[Category: Wan J]]
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[[Category: Actin binding]]
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[[Category: Yao N]]
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[[Category: Nuclear protein]]
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[[Category: Zhang M]]
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[[Category: Protein binding]]
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[[Category: Transcription]]
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Current revision

Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain

PDB ID 5y1z

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