2qvb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:41, 30 August 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal Structure of Haloalkane Dehalogenase Rv2579 from Mycobacterium tuberculosis==
==Crystal Structure of Haloalkane Dehalogenase Rv2579 from Mycobacterium tuberculosis==
-
<StructureSection load='2qvb' size='340' side='right' caption='[[2qvb]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
+
<StructureSection load='2qvb' size='340' side='right'caption='[[2qvb]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qvb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.19&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvb OCA], [https://pdbe.org/2qvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvb RCSB], [https://www.ebi.ac.uk/pdbsum/2qvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvb ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvb OCA], [http://pdbe.org/2qvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvb RCSB], [http://www.ebi.ac.uk/pdbsum/2qvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvb ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DHAA_MYCTU DHAA_MYCTU]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity).[HAMAP-Rule:MF_01231]
+
[https://www.uniprot.org/uniprot/DHAA_MYCTU DHAA_MYCTU] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity).[HAMAP-Rule:MF_01231]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvb_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvb_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 30: Line 29:
</div>
</div>
<div class="pdbe-citations 2qvb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2qvb" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Haloalkane dehalogenase]]
+
[[Category: Large Structures]]
-
[[Category: Myctu]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Cherney, M M]]
+
[[Category: Cherney MM]]
-
[[Category: Garen, C R]]
+
[[Category: Garen CR]]
-
[[Category: Hulecki, J]]
+
[[Category: Hulecki J]]
-
[[Category: James, M N.G]]
+
[[Category: James MNG]]
-
[[Category: Mazumdar, P A]]
+
[[Category: Mazumdar PA]]
-
[[Category: Structural genomic]]
+
-
[[Category: Alpha-beta hydrolase protein]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Rv2579]]
+
-
[[Category: Tbsgc]]
+

Current revision

Crystal Structure of Haloalkane Dehalogenase Rv2579 from Mycobacterium tuberculosis

PDB ID 2qvb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools