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3bjw

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==Crystal Structure of ecarpholin S complexed with suramin==
==Crystal Structure of ecarpholin S complexed with suramin==
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<StructureSection load='3bjw' size='340' side='right' caption='[[3bjw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3bjw' size='340' side='right'caption='[[3bjw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bjw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2qhg 2qhg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BJW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bjw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2qhg 2qhg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BJW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SVR:8,8-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC+ACID'>SVR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SVR:8,8-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC+ACID'>SVR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bjw OCA], [http://pdbe.org/3bjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bjw RCSB], [http://www.ebi.ac.uk/pdbsum/3bjw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bjw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bjw OCA], [https://pdbe.org/3bjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bjw RCSB], [https://www.ebi.ac.uk/pdbsum/3bjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bjw ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PA2HS_ECHCA PA2HS_ECHCA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/3bjw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/3bjw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3bjw" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3bjw" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Echis carinatus]]
[[Category: Echis carinatus]]
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[[Category: Sivaraman, J]]
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[[Category: Large Structures]]
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[[Category: Zhou, X]]
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[[Category: Sivaraman J]]
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[[Category: Calcium]]
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[[Category: Zhou X]]
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[[Category: Complex]]
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[[Category: Hydrolase]]
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[[Category: Lipid degradation]]
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[[Category: Metal-binding]]
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[[Category: Phospholipase a2]]
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[[Category: Secreted]]
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[[Category: Ser49]]
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[[Category: Snake venom]]
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[[Category: Suramin]]
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[[Category: Toxin]]
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Current revision

Crystal Structure of ecarpholin S complexed with suramin

PDB ID 3bjw

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