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3bq7

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==SAM domain of Diacylglycerol Kinase delta1 (E35G)==
==SAM domain of Diacylglycerol Kinase delta1 (E35G)==
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<StructureSection load='3bq7' size='340' side='right' caption='[[3bq7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='3bq7' size='340' side='right'caption='[[3bq7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bq7]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BQ7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bq7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BQ7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DGKD, KIAA0145 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bq7 OCA], [https://pdbe.org/3bq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bq7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bq7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bq7 OCA], [http://pdbe.org/3bq7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bq7 RCSB], [http://www.ebi.ac.uk/pdbsum/3bq7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bq7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DGKD_HUMAN DGKD_HUMAN]] May function as signaling molecule.<ref>PMID:17880279</ref> Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.<ref>PMID:17880279</ref>
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[https://www.uniprot.org/uniprot/DGKD_HUMAN DGKD_HUMAN] May function as signaling molecule.<ref>PMID:17880279</ref> Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.<ref>PMID:17880279</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/3bq7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/3bq7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3bq7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3bq7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Diacylglycerol kinase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Bowie, J U]]
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[[Category: Bowie JU]]
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[[Category: Knight, M J]]
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[[Category: Knight MJ]]
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[[Category: Sawaya, M R]]
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[[Category: Sawaya MR]]
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[[Category: Alternative splicing]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Phorbol-ester binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymerization domain]]
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[[Category: Sam domain]]
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[[Category: Transferase]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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Current revision

SAM domain of Diacylglycerol Kinase delta1 (E35G)

PDB ID 3bq7

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