3cgi

From Proteopedia

(Difference between revisions)

Current revision

Crystal structure of the PduU shell protein from the Pdu microcompartment

Structural highlights

3cgi is a 4 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.8Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDUU_SALTY

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The Pdu microcompartment is a proteinaceous, subcellular structure that serves as an organelle for the metabolism of 1,2-propanediol in Salmonella enterica. It encapsulates several related enzymes within a shell composed of a few thousand protein subunits. Recent structural studies on the carboxysome, a related microcompartment involved in CO(2) fixation, have concluded that the major shell proteins from that microcompartment form hexamers that pack into layers comprising the facets of the shell. Here we report the crystal structure of PduU, a protein from the Pdu microcompartment, representing the first structure of a shell protein from a noncarboxysome microcompartment. Though PduU is a hexamer like other characterized shell proteins, it has undergone a circular permutation leading to dramatic differences in the hexamer pore. In view of the hypothesis that microcompartment metabolites diffuse across the outer shell through these pores, the unique structure of PduU suggests the possibility of a special functional role.

Structure of the PduU shell protein from the Pdu microcompartment of Salmonella.,Crowley CS, Sawaya MR, Bobik TA, Yeates TO Structure. 2008 Sep 10;16(9):1324-32. PMID:18786396^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Crowley CS, Sawaya MR, Bobik TA, Yeates TO. Structure of the PduU shell protein from the Pdu microcompartment of Salmonella. Structure. 2008 Sep 10;16(9):1324-32. PMID:18786396 doi:10.1016/j.str.2008.05.013

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3cgi"

Categories: Large Structures | Salmonella enterica subsp. enterica serovar Typhimurium | Crowley CS | Sawaya MR | Yeates TO

@@ Line 1: / Line 1: @@
 ==Crystal structure of the PduU shell protein from the Pdu microcompartment==
-<StructureSection load='3cgi' size='340' side='right' caption='[[3cgi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+<StructureSection load='3cgi' size='340' side='right'caption='[[3cgi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3cgi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CGI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3cgi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CGI FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ewh|2ewh]], [[2a10|2a10]], [[2a1b|2a1b]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cgi OCA], [http://pdbe.org/3cgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cgi RCSB], [http://www.ebi.ac.uk/pdbsum/3cgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cgi ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cgi OCA], [https://pdbe.org/3cgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cgi RCSB], [https://www.ebi.ac.uk/pdbsum/3cgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cgi ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PDUU_SALTY PDUU_SALTY]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
   <jmolCheckbox>
-    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/3cgi_consurf.spt"</scriptWhenChecked>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/3cgi_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 30: / Line 32: @@
 __TOC__
 </StructureSection>
-[[Category: Crowley, C S]]
+[[Category: Large Structures]]
-[[Category: Sawaya, M R]]
+[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-[[Category: Yeates, T O]]
+[[Category: Crowley CS]]
-[[Category: Bacterial microcompartment]]
+[[Category: Sawaya MR]]
-[[Category: Beta barrel]]
+[[Category: Yeates TO]]
-[[Category: Circular permutation]]
-[[Category: Propanediol]]
-[[Category: Signaling protein]]
-[[Category: Unknown function]]

3cgi

From Proteopedia

Current revision

Crystal structure of the PduU shell protein from the Pdu microcompartment

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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