3cyn

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==The structure of human GPX8==
==The structure of human GPX8==
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<StructureSection load='3cyn' size='340' side='right' caption='[[3cyn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3cyn' size='340' side='right'caption='[[3cyn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3cyn]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CYN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3cyn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CYN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cyn OCA], [http://pdbe.org/3cyn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cyn RCSB], [http://www.ebi.ac.uk/pdbsum/3cyn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cyn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cyn OCA], [https://pdbe.org/3cyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cyn RCSB], [https://www.ebi.ac.uk/pdbsum/3cyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cyn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GPX8_HUMAN GPX8_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/3cyn_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/3cyn_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cyn ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cyn ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Glutathione peroxidase|Glutathione peroxidase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutathione peroxidase]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F Von]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Filippakopoulos, P]]
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[[Category: Filippakopoulos P]]
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[[Category: Johansson, C]]
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[[Category: Johansson C]]
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[[Category: Kavanagh, K L]]
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[[Category: Kavanagh KL]]
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[[Category: Kochan, G]]
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[[Category: Kochan G]]
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[[Category: Murray, J]]
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[[Category: Murray J]]
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[[Category: Oppermann, U]]
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[[Category: Oppermann U]]
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[[Category: Pike, A C.W]]
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[[Category: Pike ACW]]
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[[Category: Roos, A K]]
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[[Category: Roos AK]]
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[[Category: Structural genomic]]
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[[Category: Wikstrom M]]
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[[Category: Wikstrom, M]]
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[[Category: Yue WW]]
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[[Category: Yue, W W]]
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[[Category: Von Delft F]]
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[[Category: Membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Sgc]]
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[[Category: Thioredoxin fold]]
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[[Category: Transmembrane]]
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Current revision

The structure of human GPX8

PDB ID 3cyn

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