6bev
From Proteopedia
(Difference between revisions)
m (Protected "6bev" [edit=sysop:move=sysop]) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Single Domain Sulfurtranferase TSTD1== | |
| + | <StructureSection load='6bev' size='340' side='right'caption='[[6bev]], [[Resolution|resolution]] 1.04Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6bev]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BEV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.043Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bev OCA], [https://pdbe.org/6bev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bev RCSB], [https://www.ebi.ac.uk/pdbsum/6bev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bev ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSTD1_HUMAN TSTD1_HUMAN] Thiosulfate:glutathione sulfurtransferase (TST) required to produce glutathione persulfide (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed:24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed:24981631).<ref>PMID:24981631</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Sulfurtransferase|Sulfurtransferase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Akey DL]] | ||
| + | [[Category: Banerjee R]] | ||
| + | [[Category: Motl N]] | ||
| + | [[Category: Smith JL]] | ||
Current revision
Human Single Domain Sulfurtranferase TSTD1
| |||||||||||
