This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ig0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:57, 1 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 2.1 A resolution==
==crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 2.1 A resolution==
-
<StructureSection load='3ig0' size='340' side='right' caption='[[3ig0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='3ig0' size='340' side='right'caption='[[3ig0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ig0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IG0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IG0 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ig0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IG0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IG0 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zjt|2zjt]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB, MT0005, MTCY10H4.03, Rv0005 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ig0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ig0 OCA], [https://pdbe.org/3ig0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ig0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ig0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ig0 ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ig0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ig0 OCA], [http://pdbe.org/3ig0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ig0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ig0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ig0 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GYRB_MYCTU GYRB_MYCTU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).
+
[https://www.uniprot.org/uniprot/GYRB_MYCTU GYRB_MYCTU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/3ig0_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/3ig0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 30: Line 28:
</div>
</div>
<div class="pdbe-citations 3ig0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3ig0" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Gyrase 3D Structures|Gyrase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Myctu]]
+
[[Category: Large Structures]]
-
[[Category: Aubry, A]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Delarue, M]]
+
[[Category: Aubry A]]
-
[[Category: Mayer, C]]
+
[[Category: Delarue M]]
-
[[Category: Piton, J]]
+
[[Category: Mayer C]]
-
[[Category: Atp-binding]]
+
[[Category: Piton J]]
-
[[Category: Dna binding site]]
+
-
[[Category: Dna gyrase]]
+
-
[[Category: Gyrb]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Quinolone binding site]]
+
-
[[Category: Topoisomerase]]
+
-
[[Category: Toprim]]
+
-
[[Category: Tuberculosis]]
+
-
[[Category: Type ii topoisomerase]]
+

Current revision

crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 2.1 A resolution

PDB ID 3ig0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ig0"
Personal tools