3jvt

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==Calcium-bound Scallop Myosin Regulatory Domain (Lever Arm) with Reconstituted Complete Light Chains==
==Calcium-bound Scallop Myosin Regulatory Domain (Lever Arm) with Reconstituted Complete Light Chains==
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<StructureSection load='3jvt' size='340' side='right' caption='[[3jvt]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3jvt' size='340' side='right'caption='[[3jvt]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3jvt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Argopecten_irradians Argopecten irradians]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JVT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3jvt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Argopecten_irradians Argopecten irradians]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JVT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jtd|3jtd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvt OCA], [http://pdbe.org/3jvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jvt RCSB], [http://www.ebi.ac.uk/pdbsum/3jvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jvt ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvt OCA], [https://pdbe.org/3jvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jvt RCSB], [https://www.ebi.ac.uk/pdbsum/3jvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jvt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin. [[http://www.uniprot.org/uniprot/MLE_ARGIR MLE_ARGIR]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_ARGIR MLR_ARGIR]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
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[https://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/3jvt_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/3jvt_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3jvt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3jvt" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Argopecten irradians]]
[[Category: Argopecten irradians]]
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[[Category: Cohen, C]]
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[[Category: Large Structures]]
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[[Category: Himmel, D M]]
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[[Category: Cohen C]]
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[[Category: Mui, S]]
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[[Category: Himmel DM]]
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[[Category: Neall-Hennessey, E O]]
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[[Category: Mui S]]
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[[Category: Szent-Gyorgyi, A]]
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[[Category: O'Neall-Hennessey E]]
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[[Category: Actin-binding]]
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[[Category: Szent-Gyorgyi A]]
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[[Category: Atp-binding]]
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[[Category: Calcium]]
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[[Category: Calcium-binding protein]]
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[[Category: Calmodulin-binding]]
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[[Category: Coiled coil]]
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[[Category: Contractile protein]]
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[[Category: Cytoplasm]]
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[[Category: Motor protein]]
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[[Category: Muscle protein]]
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[[Category: Myosin]]
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[[Category: Nucleotide-binding]]
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[[Category: On-state]]
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[[Category: Regulated myosin]]
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[[Category: Scallop regulatory domain/lever arm]]
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[[Category: Smooth and molluscan muscle]]
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[[Category: Thick filament]]
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[[Category: X-ray crystallographic structure]]
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Current revision

Calcium-bound Scallop Myosin Regulatory Domain (Lever Arm) with Reconstituted Complete Light Chains

PDB ID 3jvt

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