1nkl

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==NK-LYSIN FROM PIG, NMR, 20 STRUCTURES==
==NK-LYSIN FROM PIG, NMR, 20 STRUCTURES==
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<StructureSection load='1nkl' size='340' side='right' caption='[[1nkl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1nkl' size='340' side='right'caption='[[1nkl]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nkl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NKL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nkl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NKL FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkl OCA], [http://pdbe.org/1nkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nkl RCSB], [http://www.ebi.ac.uk/pdbsum/1nkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkl ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkl OCA], [https://pdbe.org/1nkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nkl RCSB], [https://www.ebi.ac.uk/pdbsum/1nkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NKL_PIG NKL_PIG]] May be an effector molecule of cytotoxic activity. High activity against E.coli and B.megaterium, moderate against A.calcoaceticus and S.pyogenes. No activity against P.aeruginosa, S.aureus and Salmonella. Has some antifungal activity against C.albicans.
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[https://www.uniprot.org/uniprot/NKL_PIG NKL_PIG] May be an effector molecule of cytotoxic activity. High activity against E.coli and B.megaterium, moderate against A.calcoaceticus and S.pyogenes. No activity against P.aeruginosa, S.aureus and Salmonella. Has some antifungal activity against C.albicans.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkl_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 1nkl" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1nkl" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Lysin 3D structures|Lysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Liepinsh, E]]
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[[Category: Liepinsh E]]
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[[Category: Otting, G]]
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[[Category: Otting G]]
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[[Category: Antibacterial peptide]]
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[[Category: Saposin fold]]
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[[Category: Tumourolytic peptide]]
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NK-LYSIN FROM PIG, NMR, 20 STRUCTURES

PDB ID 1nkl

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