1omi
From Proteopedia
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==Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes== | ==Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes== | ||
| - | <StructureSection load='1omi' size='340' side='right' caption='[[1omi]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='1omi' size='340' side='right'caption='[[1omi]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1omi]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1omi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OMI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1omi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1omi OCA], [https://pdbe.org/1omi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1omi RCSB], [https://www.ebi.ac.uk/pdbsum/1omi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1omi ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1omi TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PRFA_LISMO PRFA_LISMO] Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/1omi_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/om/1omi_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1omi ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1omi ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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| + | ==See Also== | ||
| + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Almo | + | [[Category: Listeria monocytogenes]] |
| - | [[Category: Burley | + | [[Category: Almo SC]] |
| - | [[Category: Chance | + | [[Category: Burley SK]] |
| - | [[Category: Cossart | + | [[Category: Chance MR]] |
| - | [[Category: Dodatko | + | [[Category: Cossart P]] |
| - | [[Category: Fedorov | + | [[Category: Dodatko T]] |
| - | + | [[Category: Fedorov AA]] | |
| - | [[Category: Rajashankar | + | [[Category: Rajashankar K]] |
| - | [[Category: Thirumuruhan | + | [[Category: Thirumuruhan R]] |
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Current revision
Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes
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