1gyu

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==Gamma-adaptin appendage domain from clathrin adaptor AP1==
==Gamma-adaptin appendage domain from clathrin adaptor AP1==
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<StructureSection load='1gyu' size='340' side='right' caption='[[1gyu]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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<StructureSection load='1gyu' size='340' side='right'caption='[[1gyu]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1gyu]] is a 1 chain structure. The April 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Clathrin'' by Graham T. Johnson and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_4 10.2210/rcsb_pdb/mom_2007_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GYU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GYU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1gyu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. The April 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Clathrin'' by Graham T. Johnson and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_4 10.2210/rcsb_pdb/mom_2007_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GYU FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gyv|1gyv]], [[1gyw|1gyw]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gyu OCA], [http://pdbe.org/1gyu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gyu RCSB], [http://www.ebi.ac.uk/pdbsum/1gyu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gyu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gyu OCA], [https://pdbe.org/1gyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gyu RCSB], [https://www.ebi.ac.uk/pdbsum/1gyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gyu ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AP1G1_MOUSE AP1G1_MOUSE] Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/1gyu_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/1gyu_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1gyu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1gyu" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Adaptin 3D structures|Adaptin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Clathrin]]
[[Category: Clathrin]]
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Evans, P R]]
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[[Category: Evans PR]]
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[[Category: Kent, H M]]
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[[Category: Kent HM]]
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[[Category: McMahon, H M]]
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[[Category: McMahon HM]]
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[[Category: Owen, D J]]
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[[Category: Owen DJ]]
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[[Category: Adaptin]]
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[[Category: Adaptor]]
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[[Category: Endocytosis]]
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[[Category: Golgi]]
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Current revision

Gamma-adaptin appendage domain from clathrin adaptor AP1

PDB ID 1gyu

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