1zxj

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[[Image:1zxj.gif|left|200px]]
 
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{{Structure
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==Crystal structure of the hypthetical Mycoplasma protein, MPN555==
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|PDB= 1zxj |SIZE=350|CAPTION= <scene name='initialview01'>1zxj</scene>, resolution 2.80&Aring;
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<StructureSection load='1zxj' size='340' side='right'caption='[[1zxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1zxj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZXJ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxj OCA], [https://pdbe.org/1zxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zxj RCSB], [https://www.ebi.ac.uk/pdbsum/1zxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zxj ProSAT], [https://www.topsan.org/Proteins/BSGC/1zxj TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK01490 tig]</span>
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zxj OCA], [http://www.ebi.ac.uk/pdbsum/1zxj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zxj RCSB]</span>
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[https://www.uniprot.org/uniprot/Y555_MYCPN Y555_MYCPN]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Crystal structure of the hypthetical Mycoplasma protein, MPN555'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zxj_consurf.spt"</scriptWhenChecked>
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==Overview==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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The crystal structure of the hypothetical protein MPN555 from Mycoplasma pneumoniae (gi|1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Se-peak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3 and between lobes 2 and 3. For one of the molecules in the asymmetric unit, the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins: SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone proteins suggests an involvement in protein folding as a molecular chaperone for MPN555.
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zxj ConSurf].
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1ZXJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZXJ OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function., Schulze-Gahmen U, Aono S, Chen S, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2005 Oct;61(Pt 10):1343-7. Epub 2005, Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16204885 16204885]
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[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
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[[Category: Single protein]]
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[[Category: Aono S]]
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[[Category: Aono, S.]]
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[[Category: Kim R]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Kim S-H]]
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[[Category: Kim, R.]]
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[[Category: Schulze-Gahmen U]]
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[[Category: Kim, S H.]]
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[[Category: Shengfeng C]]
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[[Category: Schulze-Gahmen, U.]]
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[[Category: Yokota H]]
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[[Category: Shengfeng, C.]]
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[[Category: Yokota, H.]]
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[[Category: berkeley structural genomics center]]
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[[Category: bsgc]]
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[[Category: mostly alpha helical protein]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: tri-lobal structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:42:57 2008''
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Current revision

Crystal structure of the hypthetical Mycoplasma protein, MPN555

PDB ID 1zxj

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