5hd8
From Proteopedia
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==Crystal structure of disulfide cross-linked D417C ClC-ec1== | ==Crystal structure of disulfide cross-linked D417C ClC-ec1== | ||
| - | <StructureSection load='5hd8' size='340' side='right' caption='[[5hd8]], [[Resolution|resolution]] 3.15Å' scene=''> | + | <StructureSection load='5hd8' size='340' side='right'caption='[[5hd8]], [[Resolution|resolution]] 3.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5hd8]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5hd8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HD8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hd8 OCA], [https://pdbe.org/5hd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hd8 RCSB], [https://www.ebi.ac.uk/pdbsum/5hd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hd8 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Khantwal CM]] |
| - | [[Category: | + | [[Category: Maduke M]] |
| - | [[Category: | + | [[Category: Mathews II]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of disulfide cross-linked D417C ClC-ec1
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