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| - | [[Image:281d.gif|left|200px]] | |
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| - | {{Structure
| + | ==CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)== |
| - | |PDB= 281d |SIZE=350|CAPTION= <scene name='initialview01'>281d</scene>, resolution 2.380Å
| + | <StructureSection load='281d' size='340' side='right'caption='[[281d]], [[Resolution|resolution]] 2.38Å' scene=''> |
| - | |SITE=
| + | == Structural highlights == |
| - | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>
| + | <table><tr><td colspan='2'>[[281d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=281D FirstGlance]. <br> |
| - | |ACTIVITY=
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38Å</td></tr> |
| - | |GENE=
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=281d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=281d OCA], [https://pdbe.org/281d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=281d RCSB], [https://www.ebi.ac.uk/pdbsum/281d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=281d ProSAT]</span></td></tr> |
| - | |DOMAIN=
| + | </table> |
| - | |RELATEDENTRY=
| + | __TOC__ |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=281d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=281d OCA], [http://www.ebi.ac.uk/pdbsum/281d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=281d RCSB]</span>
| + | </StructureSection> |
| - | }}
| + | [[Category: Large Structures]] |
| - | | + | [[Category: Neidle S]] |
| - | '''CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)'''
| + | [[Category: Nunn CM]] |
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| - | | + | |
| - | ==Overview==
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| - | The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).
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| - | | + | |
| - | ==About this Structure==
| + | |
| - | 281D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA].
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| - | ==Reference==
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| - | Structure of the A-DNA octamer d(GGCATGCC)., Nunn CM, Neidle S, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299929 15299929]
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| - | [[Category: Protein complex]] | + | |
| - | [[Category: Neidle, S.]] | + | |
| - | [[Category: Nunn, C M.]] | + | |
| - | [[Category: a-dna]]
| + | |
| - | [[Category: double helix]]
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| - | | + | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:45:52 2008''
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