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292d

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[[Image:292d.gif|left|200px]]
 
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{{Structure
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==INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX==
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|PDB= 292d |SIZE=350|CAPTION= <scene name='initialview01'>292d</scene>, resolution 1.000&Aring;
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<StructureSection load='292d' size='340' side='right'caption='[[292d]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene>
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<table><tr><td colspan='2'>[[292d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=292D FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=292d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=292d OCA], [https://pdbe.org/292d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=292d RCSB], [https://www.ebi.ac.uk/pdbsum/292d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=292d ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=292d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=292d OCA], [http://www.ebi.ac.uk/pdbsum/292d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=292d RCSB]</span>
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__TOC__
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}}
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</StructureSection>
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[[Category: Large Structures]]
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'''INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX'''
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[[Category: Hakoshima T]]
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[[Category: Kunisawa S]]
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[[Category: Ohishi H]]
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==Overview==
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[[Category: Rich A]]
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The DNA fragment d(CG)3 was co-crystallized with N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized polyamine. The complex crystal contained one polyamine, 3 magnesium cations and one sodium cation per duplex of d(CG)3, and well diffracted the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a left-handed Z-DNA conformation, and the PA(24) molecule electrostatically interacted with the phosphate groups of the d(CG)3 duplex.
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[[Category: Tomita K]]
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[[Category: Van Boom JH]]
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==About this Structure==
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[[Category: Van Der Marel G]]
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292D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA].
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[[Category: Wang AH-J]]
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==Reference==
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Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2060642 2060642]
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[[Category: Protein complex]]
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[[Category: Boom, J H.Van.]]
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[[Category: Hakoshima, T.]]
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[[Category: Kunisawa, S.]]
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[[Category: Marel, G Van Der.]]
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[[Category: Ohishi, H.]]
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[[Category: Rich, A.]]
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[[Category: Tomita, K.]]
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[[Category: Wang, A H.J.]]
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[[Category: complexed with n-(2-aminoethyl)-1,4-diaminobutane]]
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[[Category: double helix]]
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[[Category: z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:00 2008''
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Current revision

INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX

PDB ID 292d

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