2a10

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[[Image:2a10.gif|left|200px]]
 
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{{Structure
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==carboxysome shell protein ccmK4==
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|PDB= 2a10 |SIZE=350|CAPTION= <scene name='initialview01'>2a10</scene>, resolution 1.803&Aring;
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<StructureSection load='2a10' size='340' side='right'caption='[[2a10]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2a10]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803 Synechocystis sp. PCC 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A10 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.803&#8491;</td></tr>
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|GENE= ccmK4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a10 OCA], [https://pdbe.org/2a10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a10 RCSB], [https://www.ebi.ac.uk/pdbsum/2a10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a10 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[2a18|2A18]], [[2a1b|2A1B]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a10 OCA], [http://www.ebi.ac.uk/pdbsum/2a10 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a10 RCSB]</span>
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[https://www.uniprot.org/uniprot/CCMK4_SYNY3 CCMK4_SYNY3] May be involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered (By similarity).
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a10_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a10 ConSurf].
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<div style="clear:both"></div>
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'''carboxysome shell protein ccmK4'''
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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==Overview==
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</StructureSection>
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Bacterial microcompartments are primitive organelles composed entirely of protein subunits. Genomic sequence databases reveal the widespread occurrence of microcompartments across diverse microbes. The prototypical bacterial microcompartment is the carboxysome, a protein shell for sequestering carbon fixation reactions. We report three-dimensional crystal structures of multiple carboxysome shell proteins, revealing a hexameric unit as the basic microcompartment building block and showing how these hexamers assemble to form flat facets of the polyhedral shell. The structures suggest how molecular transport across the shell may be controlled and how structural variations might govern the assembly and architecture of these subcellular compartments.
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[[Category: Large Structures]]
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[[Category: Synechocystis sp. PCC 6803]]
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==About this Structure==
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[[Category: Beeby M]]
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2A10 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A10 OCA].
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[[Category: Kerfeld CA]]
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[[Category: Nguyen CV]]
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==Reference==
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[[Category: Phillips M]]
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Protein structures forming the shell of primitive bacterial organelles., Kerfeld CA, Sawaya MR, Tanaka S, Nguyen CV, Phillips M, Beeby M, Yeates TO, Science. 2005 Aug 5;309(5736):936-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16081736 16081736]
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[[Category: Sawaya MR]]
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[[Category: Single protein]]
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[[Category: Tanaka S]]
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[[Category: Synechocystis sp.]]
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[[Category: Yeates TO]]
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[[Category: Beeby, M.]]
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[[Category: Kerfeld, C A.]]
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[[Category: Nguyen, C V.]]
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[[Category: Phillips, M.]]
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[[Category: Sawaya, M R.]]
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[[Category: Tanaka, S.]]
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[[Category: Yeates, T O.]]
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[[Category: c6 point symmetry]]
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[[Category: cyclic hexamer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:25 2008''
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Current revision

carboxysome shell protein ccmK4

PDB ID 2a10

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