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3s87

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==Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP==
==Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP==
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<StructureSection load='3s87' size='340' side='right' caption='[[3s87]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3s87' size='340' side='right'caption='[[3s87]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S87 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s87]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S87 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cvx|2cvx]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRT7, RIR1, RNR1, Saccharomyces, SDS12, YER070W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s87 OCA], [https://pdbe.org/3s87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s87 RCSB], [https://www.ebi.ac.uk/pdbsum/3s87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s87 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s87 OCA], [http://pdbe.org/3s87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s87 RCSB], [http://www.ebi.ac.uk/pdbsum/3s87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s87 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RIR1_YEAST RIR1_YEAST]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.<ref>PMID:11893751</ref>
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[https://www.uniprot.org/uniprot/RIR1_YEAST RIR1_YEAST] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.<ref>PMID:11893751</ref>
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==See Also==
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
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[[Category: Large Structures]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Ahmad, M F]]
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[[Category: Ahmad MF]]
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[[Category: Dealwis, C D]]
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[[Category: Dealwis CD]]
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[[Category: Huang, M]]
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[[Category: Huang M]]
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[[Category: Kaushal, P S]]
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[[Category: Kaushal PS]]
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[[Category: Wan, Q]]
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[[Category: Wan Q]]
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[[Category: Wijeratna, S R]]
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[[Category: Wijeratna SR]]
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[[Category: Allostery]]
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[[Category: Dntp regulation]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP

PDB ID 3s87

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