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3toz

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==2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.==
==2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.==
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<StructureSection load='3toz' size='340' side='right' caption='[[3toz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3toz' size='340' side='right'caption='[[3toz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3toz]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lismo Lismo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TOZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3toz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TOZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tnl|3tnl]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroE, lmo0490 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=169963 LISMO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3toz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3toz OCA], [https://pdbe.org/3toz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3toz RCSB], [https://www.ebi.ac.uk/pdbsum/3toz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3toz ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Shikimate_dehydrogenase Shikimate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.25 1.1.1.25] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3toz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3toz OCA], [http://pdbe.org/3toz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3toz RCSB], [http://www.ebi.ac.uk/pdbsum/3toz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3toz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AROE_LISMO AROE_LISMO]] Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).[HAMAP-Rule:MF_00222]
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[https://www.uniprot.org/uniprot/AROE_LISMO AROE_LISMO] Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).[HAMAP-Rule:MF_00222]
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==See Also==
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*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lismo]]
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[[Category: Large Structures]]
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[[Category: Shikimate dehydrogenase]]
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[[Category: Listeria monocytogenes EGD-e]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Halavaty A]]
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[[Category: Halavaty, A]]
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[[Category: Light SH]]
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[[Category: Light, S H]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Papazisi L]]
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[[Category: Papazisi, L]]
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[[Category: Shuvalova L]]
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[[Category: Shuvalova, L]]
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[[Category: Csgid]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Shikimate 5-dehydrogenase]]
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Current revision

2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.

PDB ID 3toz

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