4k0g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:52, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of human CLIC1 C24S mutant==
==Crystal structure of human CLIC1 C24S mutant==
-
<StructureSection load='4k0g' size='340' side='right' caption='[[4k0g]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
+
<StructureSection load='4k0g' size='340' side='right'caption='[[4k0g]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4k0g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K0G FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4k0g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K0G FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jzq|4jzq]], [[4k0n|4k0n]], [[4k1d|4k1d]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLIC1, CLIC1 G6 NCC27, G6, NCC27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0g OCA], [https://pdbe.org/4k0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k0g RCSB], [https://www.ebi.ac.uk/pdbsum/4k0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0g ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0g OCA], [http://pdbe.org/4k0g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k0g RCSB], [http://www.ebi.ac.uk/pdbsum/4k0g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0g ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
+
[https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
 +
 
 +
==See Also==
 +
*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Curmi, P M.G]]
+
[[Category: Large Structures]]
-
[[Category: Duff, A P]]
+
[[Category: Curmi PMG]]
-
[[Category: Harrop, S J]]
+
[[Category: Duff AP]]
-
[[Category: Phang, J M]]
+
[[Category: Harrop SJ]]
-
[[Category: Wilk, K E]]
+
[[Category: Phang JM]]
-
[[Category: Chloride ion channel]]
+
[[Category: Wilk KE]]
-
[[Category: Clic]]
+
-
[[Category: Glutathione-s-transferase fold]]
+
-
[[Category: Transport protein]]
+

Current revision

Crystal structure of human CLIC1 C24S mutant

PDB ID 4k0g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4k0g"
Personal tools