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4kxh

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Current revision (09:20, 7 December 2022) (edit) (undo)
 
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==The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease==
==The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease==
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<StructureSection load='4kxh' size='340' side='right' caption='[[4kxh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='4kxh' size='340' side='right'caption='[[4kxh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kxh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KXH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kxh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KXH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASE1, RIB1, RNS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxh OCA], [https://pdbe.org/4kxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kxh RCSB], [https://www.ebi.ac.uk/pdbsum/4kxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxh ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kxh OCA], [http://pdbe.org/4kxh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kxh RCSB], [http://www.ebi.ac.uk/pdbsum/4kxh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kxh ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNAS1_HUMAN RNAS1_HUMAN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:17350650</ref>
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[https://www.uniprot.org/uniprot/RNAS1_HUMAN RNAS1_HUMAN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:17350650</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Temp|Temp]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Pancreatic ribonuclease]]
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[[Category: Large Structures]]
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[[Category: Mazzarella, L]]
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[[Category: Mazzarella L]]
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[[Category: Merlino, A]]
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[[Category: Merlino A]]
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[[Category: Pica, A]]
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[[Category: Pica A]]
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[[Category: Sica, F]]
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[[Category: Sica F]]
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[[Category: Hydrolase]]
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Current revision

The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease

PDB ID 4kxh

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