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1amh

From Proteopedia

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==UNCOMPLEXED RAT TRYPSIN MUTANT WITH ASP 189 REPLACED WITH SER (D189S)==
==UNCOMPLEXED RAT TRYPSIN MUTANT WITH ASP 189 REPLACED WITH SER (D189S)==
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<StructureSection load='1amh' size='340' side='right' caption='[[1amh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='1amh' size='340' side='right'caption='[[1amh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1amh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AMH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1amh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AMH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1amh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1amh OCA], [http://pdbe.org/1amh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1amh RCSB], [http://www.ebi.ac.uk/pdbsum/1amh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1amh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1amh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1amh OCA], [https://pdbe.org/1amh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1amh RCSB], [https://www.ebi.ac.uk/pdbsum/1amh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1amh ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY2_RAT TRY2_RAT]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/1amh_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/1amh_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1amh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1amh" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Black rat]]
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[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Rattus rattus]]
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[[Category: Bocskei, Z S]]
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[[Category: Bocskei ZS]]
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[[Category: Graf, L]]
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[[Category: Graf L]]
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[[Category: Naray-Szabo, G]]
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[[Category: Naray-Szabo G]]
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[[Category: Szabo, E]]
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[[Category: Szabo E]]
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[[Category: Activation domain]]
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[[Category: Hydrolase]]
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[[Category: Serine protease]]
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[[Category: Substrate specificity hydrolase]]
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Current revision

UNCOMPLEXED RAT TRYPSIN MUTANT WITH ASP 189 REPLACED WITH SER (D189S)

PDB ID 1amh

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