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1qwx
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==Crystal Structure of a Staphylococcal Inhibitor/Chaperone== | ==Crystal Structure of a Staphylococcal Inhibitor/Chaperone== | ||
| - | <StructureSection load='1qwx' size='340' side='right' caption='[[1qwx]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='1qwx' size='340' side='right'caption='[[1qwx]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1qwx]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1qwx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QWX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qwx OCA], [https://pdbe.org/1qwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qwx RCSB], [https://www.ebi.ac.uk/pdbsum/1qwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qwx ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SSPC_STAAW SSPC_STAAW]] Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity). |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Brown | + | [[Category: Staphylococcus aureus subsp. aureus MW2]] |
| - | [[Category: Earhart | + | [[Category: Brown CK]] |
| - | [[Category: Gu | + | [[Category: Earhart CA]] |
| - | [[Category: McGavin | + | [[Category: Gu Z-Y]] |
| - | [[Category: Nickerson | + | [[Category: McGavin MJ]] |
| - | [[Category: Ohlendorf | + | [[Category: Nickerson N]] |
| - | + | [[Category: Ohlendorf DH]] | |
| - | + | ||
Current revision
Crystal Structure of a Staphylococcal Inhibitor/Chaperone
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