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6ay1

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==Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori==
==Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori==
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<StructureSection load='6ay1' size='340' side='right' caption='[[6ay1]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='6ay1' size='340' side='right'caption='[[6ay1]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ay1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AY1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ay1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AY1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ndk, HPG27_182 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ay1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay1 OCA], [https://pdbe.org/6ay1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ay1 RCSB], [https://www.ebi.ac.uk/pdbsum/6ay1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ay1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ay1 OCA], [http://pdbe.org/6ay1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ay1 RCSB], [http://www.ebi.ac.uk/pdbsum/6ay1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ay1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NDK_HELPG NDK_HELPG]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
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[https://www.uniprot.org/uniprot/NDK_HELPG NDK_HELPG] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
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==See Also==
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43504]]
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[[Category: Helicobacter pylori]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Edwards, T E]]
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[[Category: Edwards TE]]
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[[Category: Structural genomic]]
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[[Category: Atp-dependent]]
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[[Category: Kinase]]
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[[Category: Ndk]]
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[[Category: Ndpk]]
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[[Category: Niaid]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a nucleoside diphosphate kinase NDK from Helicobacter pylori

PDB ID 6ay1

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