4nnt

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==Crystal structure of FABP4 in complex with novel inhibitor==
==Crystal structure of FABP4 in complex with novel inhibitor==
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<StructureSection load='4nnt' size='340' side='right' caption='[[4nnt]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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<StructureSection load='4nnt' size='340' side='right'caption='[[4nnt]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nnt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nnt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=76D:2,4,6-TRI(PROPAN-2-YL)BENZOIC+ACID'>76D</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nns|4nns]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=76D:2,4,6-TRI(PROPAN-2-YL)BENZOIC+ACID'>76D</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnt OCA], [https://pdbe.org/4nnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnt RCSB], [https://www.ebi.ac.uk/pdbsum/4nnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnt ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnt OCA], [http://pdbe.org/4nnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnt RCSB], [http://www.ebi.ac.uk/pdbsum/4nnt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnt ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN]] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
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[https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
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==See Also==
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*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Chen, T T]]
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[[Category: Large Structures]]
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[[Category: Liu, Q F]]
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[[Category: Chen TT]]
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[[Category: Xu, Y C]]
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[[Category: Liu QF]]
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[[Category: Fabp4 inhibitor]]
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[[Category: Xu YC]]
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[[Category: Lipid binding protein-inhibitor complex]]
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Current revision

Crystal structure of FABP4 in complex with novel inhibitor

PDB ID 4nnt

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