4aj3

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==3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex==
==3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex==
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<StructureSection load='4aj3' size='340' side='right' caption='[[4aj3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4aj3' size='340' side='right'caption='[[4aj3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4aj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJ3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4aj3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJ3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4aja|4aja]], [[4ajb|4ajb]], [[4ajc|4ajc]], [[4ajs|4ajs]], [[4ajr|4ajr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aj3 OCA], [https://pdbe.org/4aj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aj3 RCSB], [https://www.ebi.ac.uk/pdbsum/4aj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aj3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aj3 OCA], [http://pdbe.org/4aj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4aj3 RCSB], [http://www.ebi.ac.uk/pdbsum/4aj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4aj3 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IDH_ECOLI IDH_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4aj3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4aj3" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Carrondo, M A]]
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[[Category: Large Structures]]
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[[Category: Dean, A M]]
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[[Category: Carrondo MA]]
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[[Category: Goncalves, S]]
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[[Category: Dean AM]]
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[[Category: Matias, P M]]
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[[Category: Goncalves S]]
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[[Category: Miller, S P]]
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[[Category: Matias PM]]
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[[Category: Oxidative beta-decarboxylation]]
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[[Category: Miller SP]]
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[[Category: Oxidoreductase]]
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Current revision

3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex

PDB ID 4aj3

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