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4wyz

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==The crystal structure of the A109G mutant of RNase A in complex with 3'UMP==
==The crystal structure of the A109G mutant of RNase A in complex with 3'UMP==
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<StructureSection load='4wyz' size='340' side='right' caption='[[4wyz]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='4wyz' size='340' side='right'caption='[[4wyz]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WYZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wyz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WYZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U3P:3-URIDINEMONOPHOSPHATE'>U3P</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U3P:3-URIDINEMONOPHOSPHATE'>U3P</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wyn|4wyn]], [[4wyp|4wyp]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyz OCA], [https://pdbe.org/4wyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wyz RCSB], [https://www.ebi.ac.uk/pdbsum/4wyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyz ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASE1, RNS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyz OCA], [http://pdbe.org/4wyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wyz RCSB], [http://www.ebi.ac.uk/pdbsum/4wyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4wyz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4wyz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
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[[Category: Pancreatic ribonuclease]]
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[[Category: Large Structures]]
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[[Category: Doucet, N]]
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[[Category: Doucet N]]
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[[Category: French, R L]]
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[[Category: French RL]]
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[[Category: Gagne, D]]
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[[Category: Gagne D]]
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[[Category: Simonovic, M]]
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[[Category: Simonovic M]]
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[[Category: Conformational dynamic]]
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[[Category: Hydrolase]]
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Current revision

The crystal structure of the A109G mutant of RNase A in complex with 3'UMP

PDB ID 4wyz

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