4x2q
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2== | ==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2== | ||
| - | <StructureSection load='4x2q' size='340' side='right' caption='[[4x2q]], [[Resolution|resolution]] 2.94Å' scene=''> | + | <StructureSection load='4x2q' size='340' side='right'caption='[[4x2q]], [[Resolution|resolution]] 2.94Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X2Q FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2q OCA], [https://pdbe.org/4x2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x2q RCSB], [https://www.ebi.ac.uk/pdbsum/4x2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x2q ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/AL1A2_HUMAN AL1A2_HUMAN] Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). |
| + | |||
| + | ==See Also== | ||
| + | *[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Amory | + | [[Category: Amory JK]] |
| - | [[Category: Goldstein | + | [[Category: Goldstein AS]] |
| - | + | [[Category: Le Trong I]] | |
| - | + | [[Category: Paik J]] | |
| - | [[Category: Trong | + | [[Category: Stenkamp RE]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2
| |||||||||||
