2aqs

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[[Image:2aqs.jpg|left|200px]]
 
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{{Structure
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==CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant==
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|PDB= 2aqs |SIZE=350|CAPTION= <scene name='initialview01'>2aqs</scene>, resolution 1.70&Aring;
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<StructureSection load='2aqs' size='340' side='right'caption='[[2aqs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2aqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQS FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE= sodC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=487 Neisseria meningitidis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqs OCA], [https://pdbe.org/2aqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqs RCSB], [https://www.ebi.ac.uk/pdbsum/2aqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqs ProSAT]</span></td></tr>
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|RELATEDENTRY=[[2aqm|2AQM]], [[2aqn|2AQN]], [[2aqp|2AQP]], [[2aqq|2AQQ]], [[2aqr|2AQR]], [[2aqt|2AQT]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqs OCA], [http://www.ebi.ac.uk/pdbsum/2aqs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2aqs RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/SODC_NEIMB SODC_NEIMB] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aqs ConSurf].
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<div style="clear:both"></div>
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'''CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant'''
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==See Also==
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2AQS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQS OCA].
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[[Category: Large Structures]]
[[Category: Neisseria meningitidis]]
[[Category: Neisseria meningitidis]]
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[[Category: Single protein]]
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[[Category: Bruns CK]]
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[[Category: Superoxide dismutase]]
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[[Category: Cabelli DE]]
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[[Category: Bruns, C K.]]
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[[Category: Cao Z]]
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[[Category: Cabelli, D E.]]
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[[Category: DiDonato M]]
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[[Category: Cao, Z.]]
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[[Category: Getzoff ED]]
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[[Category: DiDonato, M.]]
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[[Category: Kassmann CJ]]
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[[Category: Getzoff, E D.]]
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[[Category: Kroll JS]]
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[[Category: Kassmann, C J.]]
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[[Category: Tabatabai LB]]
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[[Category: Kroll, J S.]]
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[[Category: Tabatabai, L B.]]
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[[Category: cu/zn superoxide dismutase]]
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[[Category: electrostatic guidance]]
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[[Category: neisseria meningitidi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:56:03 2008''
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Current revision

CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant

PDB ID 2aqs

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