5h8a
From Proteopedia
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==Mmi1 YTH domain== | ==Mmi1 YTH domain== | ||
| - | <StructureSection load='5h8a' size='340' side='right' caption='[[5h8a]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='5h8a' size='340' side='right'caption='[[5h8a]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5h8a]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5h8a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5H8A FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.751Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5h8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h8a OCA], [https://pdbe.org/5h8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5h8a RCSB], [https://www.ebi.ac.uk/pdbsum/5h8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5h8a ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MMI1_SCHPO MMI1_SCHPO] RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs (By similarity). Required for elemination of certain meiosis-specific mRNAs in an early event following transcription. May bind to the cis-acting region (DSR) of the mRNA, activating the nuclear exosome which may lead to the degradation of the transcript from the 3' region (PubMed:16823445).[UniProtKB:Q06390]<ref>PMID:16823445</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Schizosaccharomyces pombe 972h-]] |
| - | [[Category: | + | [[Category: Chatterjee D]] |
| - | [[Category: | + | [[Category: Goldgur Y]] |
| - | [[Category: | + | [[Category: Shuman S]] |
| - | + | ||
Current revision
Mmi1 YTH domain
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