5t8z

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==Crystal structure of a peptide deformylase from Burkholderia multivorans in complex with actinonin==
==Crystal structure of a peptide deformylase from Burkholderia multivorans in complex with actinonin==
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<StructureSection load='5t8z' size='340' side='right' caption='[[5t8z]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='5t8z' size='340' side='right'caption='[[5t8z]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5t8z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burm1 Burm1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T8Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5t8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_multivorans_ATCC_17616 Burkholderia multivorans ATCC 17616]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T8Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">def, BMULJ_01994 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=395019 BURM1])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t8z OCA], [https://pdbe.org/5t8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t8z RCSB], [https://www.ebi.ac.uk/pdbsum/5t8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t8z ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t8z OCA], [http://pdbe.org/5t8z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t8z RCSB], [http://www.ebi.ac.uk/pdbsum/5t8z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t8z ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0H3KPJ9_BURM1 A0A0H3KPJ9_BURM1]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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[https://www.uniprot.org/uniprot/A0A0H3KPJ9_BURM1 A0A0H3KPJ9_BURM1] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Burm1]]
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[[Category: Burkholderia multivorans ATCC 17616]]
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[[Category: Peptide deformylase]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Actinonin]]
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[[Category: Burkholderia multivoran]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Ssgcid]]
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Current revision

Crystal structure of a peptide deformylase from Burkholderia multivorans in complex with actinonin

PDB ID 5t8z

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