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5tua

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==structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1==
==structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1==
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<StructureSection load='5tua' size='340' side='right' caption='[[5tua]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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<StructureSection load='5tua' size='340' side='right'caption='[[5tua]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TUA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TUA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPC1, CCH1, FOU2, At4g03560, F9H3.19, T5L23.5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tua OCA], [http://pdbe.org/5tua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tua RCSB], [http://www.ebi.ac.uk/pdbsum/5tua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tua ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tua OCA], [https://pdbe.org/5tua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tua RCSB], [https://www.ebi.ac.uk/pdbsum/5tua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TPC1_ARATH TPC1_ARATH]] Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane. Is one of the essential components of the slow vacuolar (SV) channel. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Involved in the regulation of germination and stomatal movement.<ref>PMID:15464979</ref> <ref>PMID:15772667</ref>
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[https://www.uniprot.org/uniprot/TPC1_ARATH TPC1_ARATH] Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane. Is one of the essential components of the slow vacuolar (SV) channel. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Involved in the regulation of germination and stomatal movement.<ref>PMID:15464979</ref> <ref>PMID:15772667</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5tua" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5tua" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Guo, J]]
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[[Category: Large Structures]]
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[[Category: Jiang, Y]]
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[[Category: Guo J]]
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[[Category: Zeng, W]]
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[[Category: Jiang Y]]
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[[Category: Membrane protein]]
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[[Category: Zeng W]]
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[[Category: Metal transport]]
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[[Category: Na+-selective]]
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[[Category: Two-pore channel]]
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Current revision

structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1

PDB ID 5tua

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