5urq

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==Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176==
==Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176==
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<StructureSection load='5urq' size='340' side='right' caption='[[5urq]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='5urq' size='340' side='right'caption='[[5urq]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5urq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_jejuni Campylobacter jejuni jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5URQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5URQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5urq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni Campylobacter jejuni subsp. jejuni] and [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_CG8486 Campylobacter jejuni subsp. jejuni CG8486]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5URQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5URQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8L7:N-{2-CHLORO-5-[({2-[3-(PROP-1-EN-2-YL)PHENYL]PROPAN-2-YL}CARBAMOYL)AMINO]PHENYL}-ALPHA-D-RIBOFURANOSYLAMINE'>8L7</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r7j|4r7j]], [[4mz1|4mz1]], [[4mz8|4mz8]], [[5uqf|5uqf]], [[5uqg|5uqg]], [[5uqh|5uqh]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8L7:N-{2-CHLORO-5-[({2-[3-(PROP-1-EN-2-YL)PHENYL]PROPAN-2-YL}CARBAMOYL)AMINO]PHENYL}-ALPHA-D-RIBOFURANOSYLAMINE'>8L7</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaB, Cj8486_1016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32022 Campylobacter jejuni jejuni])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5urq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5urq OCA], [https://pdbe.org/5urq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5urq RCSB], [https://www.ebi.ac.uk/pdbsum/5urq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5urq ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5urq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5urq OCA], [http://pdbe.org/5urq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5urq RCSB], [http://www.ebi.ac.uk/pdbsum/5urq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5urq ProSAT]</span></td></tr>
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</table>
</table>
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==See Also==
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*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Campylobacter jejuni jejuni]]
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[[Category: Campylobacter jejuni subsp. jejuni]]
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[[Category: IMP dehydrogenase]]
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[[Category: Campylobacter jejuni subsp. jejuni CG8486]]
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Anderson WF]]
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[[Category: Gollapalli, D]]
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[[Category: Gollapalli D]]
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[[Category: Gu, M]]
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[[Category: Gu M]]
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[[Category: Hedstrom, L]]
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[[Category: Hedstrom L]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Kim, Y]]
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[[Category: Kim Y]]
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[[Category: Makowska-Grzyska, M]]
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[[Category: Makowska-Grzyska M]]
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[[Category: Maltseva, N]]
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[[Category: Maltseva N]]
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[[Category: Csgid]]
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[[Category: Delta cb]]
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[[Category: Impdh]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Tim barrel]]
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Current revision

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p176

PDB ID 5urq

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