3d3c

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==Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.==
==Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.==
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<StructureSection load='3d3c' size='340' side='right' caption='[[3d3c]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='3d3c' size='340' side='right'caption='[[3d3c]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d3c]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D3C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d3c]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D3C FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3d3b|3d3b]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nusB, ssyB, b0416, JW0406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), rpsJ, nusE, b3321, JW3283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3c OCA], [https://pdbe.org/3d3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d3c RCSB], [https://www.ebi.ac.uk/pdbsum/3d3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3c OCA], [http://pdbe.org/3d3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d3c RCSB], [http://www.ebi.ac.uk/pdbsum/3d3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d3c ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUSB_ECOLI NUSB_ECOLI]] One of the proteins essential for the formation of the RNA polymerase antitermination complex in the presence of lambda phage N protein. However, it is involved in the transcription termination process at certain sites during normal bacterial growth. Binds to the BoxA RNA motif. [[http://www.uniprot.org/uniprot/RS10_ECOLI RS10_ECOLI]] Involved in the binding of tRNA to the ribosomes.[HAMAP-Rule:MF_00508]
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[https://www.uniprot.org/uniprot/NUSB_ECOLI NUSB_ECOLI] One of the proteins essential for the formation of the RNA polymerase antitermination complex in the presence of lambda phage N protein. However, it is involved in the transcription termination process at certain sites during normal bacterial growth. Binds to the BoxA RNA motif.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/3d3c_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/3d3c_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3d3c" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3d3c" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosomal protein S10|Ribosomal protein S10]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Luo, X]]
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[[Category: Large Structures]]
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[[Category: Wahl, M C]]
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[[Category: Luo X]]
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[[Category: Lambda n antitermination]]
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[[Category: Wahl MC]]
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[[Category: Nusb]]
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[[Category: Nuse]]
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[[Category: Nut]]
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[[Category: Phage lambda]]
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[[Category: Ribonucleoprotein]]
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[[Category: Ribosomal protein]]
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[[Category: Rna-binding]]
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[[Category: Rrn antitermination]]
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[[Category: S10]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription termination]]
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Current revision

Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.

PDB ID 3d3c

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