4css
From Proteopedia
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==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside== | ==Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside== | ||
- | <StructureSection load='4css' size='340' side='right' caption='[[4css]], [[Resolution|resolution]] 1.07Å' scene=''> | + | <StructureSection load='4css' size='340' side='right'caption='[[4css]], [[Resolution|resolution]] 1.07Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4css]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CSS FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.069Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWX:4-(ALPHA-D-MANNOPYRANOSYLOXY)-BIPHENYL-4-METHYL+SULFONAMIDE'>CWX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4css FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4css OCA], [https://pdbe.org/4css PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4css RCSB], [https://www.ebi.ac.uk/pdbsum/4css PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4css ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4css" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4css" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Adhesin 3D structures|Adhesin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Escherichia coli K-12]] |
- | [[Category: Abgottspon | + | [[Category: Large Structures]] |
- | [[Category: Eris | + | [[Category: Abgottspon D]] |
- | [[Category: Ernst | + | [[Category: Eris D]] |
- | [[Category: Hutter | + | [[Category: Ernst B]] |
- | [[Category: Jakob | + | [[Category: Hutter A]] |
- | [[Category: Jian | + | [[Category: Jakob RP]] |
- | [[Category: Kleeb | + | [[Category: Jian X]] |
- | [[Category: Luedin | + | [[Category: Kleeb S]] |
- | [[Category: Maier | + | [[Category: Luedin N]] |
- | [[Category: Mayer | + | [[Category: Maier T]] |
- | [[Category: Navarra | + | [[Category: Mayer K]] |
- | [[Category: Pang | + | [[Category: Navarra G]] |
- | [[Category: Preston | + | [[Category: Pang L]] |
- | [[Category: Rabbani | + | [[Category: Preston RC]] |
- | [[Category: Scharenberg | + | [[Category: Rabbani S]] |
- | [[Category: Schwardt | + | [[Category: Scharenberg M]] |
- | [[Category: Sharpe | + | [[Category: Schwardt O]] |
- | [[Category: Sigl | + | [[Category: Sharpe T]] |
- | [[Category: Smiesko | + | [[Category: Sigl A]] |
- | [[Category: Zihlmann | + | [[Category: Smiesko M]] |
- | + | [[Category: Zihlmann P]] | |
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Current revision
Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside
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Categories: Escherichia coli K-12 | Large Structures | Abgottspon D | Eris D | Ernst B | Hutter A | Jakob RP | Jian X | Kleeb S | Luedin N | Maier T | Mayer K | Navarra G | Pang L | Preston RC | Rabbani S | Scharenberg M | Schwardt O | Sharpe T | Sigl A | Smiesko M | Zihlmann P