4ndz
From Proteopedia
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==Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP== | ==Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP== | ||
- | <StructureSection load='4ndz' size='340' side='right' caption='[[4ndz]], [[Resolution|resolution]] 3.45Å' scene=''> | + | <StructureSection load='4ndz' size='340' side='right'caption='[[4ndz]], [[Resolution|resolution]] 3.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4ndz]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ndz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UMEA_3304-1 Escherichia coli UMEA 3304-1] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NDZ FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GNS:N-SULFO-ALPHA-D-GLUCOSAMINE'>GNS</scene>, <scene name='pdbligand=IDR:L-IDURONIC+ACID'>IDR</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>< | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.45Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GNS:N-SULFO-ALPHA-D-GLUCOSAMINE'>GNS</scene>, <scene name='pdbligand=IDR:L-IDURONIC+ACID'>IDR</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ndz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ndz OCA], [https://pdbe.org/4ndz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ndz RCSB], [https://www.ebi.ac.uk/pdbsum/4ndz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ndz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/HS2ST_CHICK HS2ST_CHICK] Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes.<ref>PMID:19022906</ref> |
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Escherichia coli UMEA 3304-1]] |
- | [[Category: | + | [[Category: Gallus gallus]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Hsieh P]] |
- | [[Category: | + | [[Category: Krahn JM]] |
- | [[Category: | + | [[Category: Liu C]] |
- | [[Category: | + | [[Category: Liu J]] |
- | + | [[Category: Pedersen LC]] | |
- | [[Category: | + | [[Category: Perera L]] |
- | [[Category: | + | [[Category: Sheng J]] |
- | [[Category: | + | [[Category: Xu Y]] |
- | [[Category: | + |
Current revision
Structure of Maltose Binding Protein fusion to 2-O-Sulfotransferase with bound heptasaccharide and PAP
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Categories: Escherichia coli UMEA 3304-1 | Gallus gallus | Large Structures | Hsieh P | Krahn JM | Liu C | Liu J | Pedersen LC | Perera L | Sheng J | Xu Y