2vaz
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.== | ==Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.== | ||
| - | < | + | <SX load='2vaz' size='340' side='right' viewer='molstar' caption='[[2vaz]], [[Resolution|resolution]] 10.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2vaz]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2vaz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vaz OCA], [https://pdbe.org/2vaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vaz RCSB], [https://www.ebi.ac.uk/pdbsum/2vaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vaz ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RS15_ECOLI RS15_ECOLI] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.[HAMAP-Rule:MF_01343] In the E.coli 70S ribosome it has been modeled (PubMed:12809609) to contact the 23S rRNA of the 50S subunit forming part of bridge B4. In the two 3.5 A resolved ribosome structures (PubMed:16272117) there are minor differences between side-chain conformations.[HAMAP-Rule:MF_01343] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vaz_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vaz_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 26: | Line 28: | ||
</div> | </div> | ||
<div class="pdbe-citations 2vaz" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2vaz" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ribosomal protein S15|Ribosomal protein S15]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: Ehresmann | + | [[Category: Large Structures]] |
| - | [[Category: Klaholz | + | [[Category: Ehresmann C]] |
| - | [[Category: Marzi | + | [[Category: Klaholz BP]] |
| - | [[Category: Myasnikov | + | [[Category: Marzi S]] |
| - | [[Category: Romby | + | [[Category: Myasnikov AG]] |
| - | [[Category: Serganov | + | [[Category: Romby P]] |
| - | [[Category: Yusupov | + | [[Category: Serganov A]] |
| - | + | [[Category: Yusupov M]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.
| |||||||||
