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3e2n

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==Engineering ascorbate peroxidase activity into cytochrome c peroxidase==
==Engineering ascorbate peroxidase activity into cytochrome c peroxidase==
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<StructureSection load='3e2n' size='340' side='right' caption='[[3e2n]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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<StructureSection load='3e2n' size='340' side='right'caption='[[3e2n]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3e2n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Garden_pea Garden pea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E2N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3e2n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E2N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E2N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dso|1dso]], [[2v23|2v23]], [[1dsg|1dsg]], [[5ccp|5ccp]], [[1zby|1zby]], [[3e2o|3e2o]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APX1,APPX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3888 Garden pea])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e2n OCA], [https://pdbe.org/3e2n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e2n RCSB], [https://www.ebi.ac.uk/pdbsum/3e2n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e2n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e2n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e2n OCA], [http://pdbe.org/3e2n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e2n RCSB], [http://www.ebi.ac.uk/pdbsum/3e2n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e2n ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
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[https://www.uniprot.org/uniprot/APX1_PEA APX1_PEA] Plays a key role in hydrogen peroxide removal.[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e2n_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e2/3e2n_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 3e2n" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3e2n" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cytochrome c peroxidase 3D structures|Cytochrome c peroxidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Garden pea]]
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[[Category: Large Structures]]
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[[Category: Meharenna, Y T]]
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[[Category: Pisum sativum]]
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[[Category: Oertel, P]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Poulos, T L]]
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[[Category: Meharenna YT]]
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[[Category: Oxidoreductase]]
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[[Category: Oertel P]]
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[[Category: Poulos TL]]

Current revision

Engineering ascorbate peroxidase activity into cytochrome c peroxidase

PDB ID 3e2n

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