4kcc

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==Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State==
==Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State==
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<StructureSection load='4kcc' size='340' side='right' caption='[[4kcc]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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<StructureSection load='4kcc' size='340' side='right'caption='[[4kcc]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kcc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KCC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kcc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KCC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.894&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pb7|1pb7]], [[1pb8|1pb8]], [[1pbq|1pbq]], [[4kcd|4kcd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcc OCA], [http://pdbe.org/4kcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kcc RCSB], [http://www.ebi.ac.uk/pdbsum/4kcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kcc OCA], [https://pdbe.org/4kcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kcc RCSB], [https://www.ebi.ac.uk/pdbsum/4kcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kcc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>
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[https://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4kcc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4kcc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Glutamate receptor 3D structures|Glutamate receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Berger, A J]]
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[[Category: Large Structures]]
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[[Category: Lau, A Y]]
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[[Category: Rattus norvegicus]]
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[[Category: Mayer, M L]]
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[[Category: Berger AJ]]
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[[Category: Membrane protein]]
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[[Category: Lau AY]]
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[[Category: Mayer ML]]

Current revision

Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State

PDB ID 4kcc

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