3n94
From Proteopedia
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==Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain== | ==Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain== | ||
- | <StructureSection load='3n94' size='340' side='right' caption='[[3n94]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='3n94' size='340' side='right'caption='[[3n94]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3n94]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3n94]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N94 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n94 OCA], [https://pdbe.org/3n94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n94 RCSB], [https://www.ebi.ac.uk/pdbsum/3n94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n94 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/PACR_HUMAN PACR_HUMAN] This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3n94" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3n94" style="background-color:#fffaf0;"></div> | ||
+ | |||
+ | ==See Also== | ||
+ | *[[Hormone|Hormone]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Escherichia coli K-12]] |
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Kumar S]] |
- | [[Category: | + | [[Category: Pioszak AA]] |
- | [[Category: | + | [[Category: Swaminathan K]] |
- | [[Category: | + | [[Category: Xu HE]] |
- | + | ||
- | + |
Current revision
Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain
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