4qzd
From Proteopedia
(Difference between revisions)
(One intermediate revision not shown.) | |||
Line 1: | Line 1: | ||
==Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-C base pair== | ==Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-C base pair== | ||
- | <StructureSection load='4qzd' size='340' side='right' caption='[[4qzd]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='4qzd' size='340' side='right'caption='[[4qzd]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4qzd]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qzd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QZD FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
- | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qzd OCA], [https://pdbe.org/4qzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qzd RCSB], [https://www.ebi.ac.uk/pdbsum/4qzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qzd ProSAT]</span></td></tr> |
- | < | + | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Line 25: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Mus musculus]] |
- | [[Category: Delarue | + | [[Category: Delarue M]] |
- | [[Category: Gouge | + | [[Category: Gouge J]] |
- | + | ||
- | + | ||
- | + |
Current revision
Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-C base pair
|